Interaction of phenol derivatives with ion channels
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چکیده
منابع مشابه
Interaction of phenol derivatives with ion channels
Phenols began to play a prominent role very early in modern operative medicine in the 1860s when Lister introduced his ‘antisepsis’ approach. The treatment of open wounds by carbolic acid dramatically reduced morbidity and mortality of surgical patients for the first time [1]. This central place in operative medicine was lost when, in the early 20th Century, ‘asepsis’ replaced ‘antisepsis’. The...
متن کاملInteraction of phenol derivatives with ion channels.
Phenols began to play a prominent role very early in modern operative medicine in the 1860s when Lister introduced his ‘antisepsis’ approach. The treatment of open wounds by carbolic acid dramatically reduced morbidity and mortality of surgical patients for the first time [1]. This central place in operative medicine was lost when, in the early 20th Century, ‘asepsis’ replaced ‘antisepsis’. The...
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A number of compounds related to TEA(+) (tetraethylammoniumion) were injected into squid axons and their effects on g(K) (the potassium conductance) were determined. In most of these ions a quaternary nitrogen is surrounded by three ethyl groups and a fourth group that is very hydrophobic. Several of the ions cause inactivation of g(K), a type of ionic gating that is not normally seen in squid ...
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The interaction of ion channels with the actin-based cytoskeleton in epithelial cells not only maintains the polarized expression of ion channels within specific membrane domains, it also functions in the intracellular trafficking and regulation of channel activity. Initial evidence supporting an interaction between epithelial ion channels and the actin-based cytoskeleton came from patch-clamp ...
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ژورنال
عنوان ژورنال: European Journal of Anaesthesiology
سال: 2002
ISSN: 0265-0215,1365-2346
DOI: 10.1017/s0265021502000017